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. 2020 Mar 17;21(6):2061. doi: 10.3390/ijms21062061

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The role of PPARβ/δ in hepatic lipid metabolism. Enzymes/proteins up-regulated by PPARβ/δ activation are indicated as green boxes. ACACA, acetyl-CoA carboxylase 1; ACACB, acetyl-CoA carboxylase 2; ACLY, ATP citrate lyase; ACOT1, acyl-CoA thioesterase 1; CD36, cluster of differentiation 36; CPT1A, carnitine palmitoyltransferase I; ELOVL6, elongation of very long chain fatty acid-like family member 6; FASN, fatty acid synthase; GPAT3, glycerol-3-phosphate acyltransferase 3; NADPH, nicotinamide adenine dinucleotide phosphate; NEFA, non-esterified fatty acid; PEPCK, phosphoenolpyruvate carboxykinase; PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGD, phosphogluconate dehydrogenase; PLTP, phospholipid transfer protein; SCD2, stearoyl-CoA desaturase 2; TAG, triacylglycerol; VLDL, very low density lipoprotein; VLDLR, VLDL receptor.