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. 2020 Feb 25;12(3):529. doi: 10.3390/cancers12030529

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

miR-375 target genes are involved in Hippo and epithelial to mesenchymal transition (EMT) signaling pathways in MCC cells. (a) Gene ontology analysis was performed in Metascape using the top 500 predicted miR-375 target genes. (b) Gene set enrichment analysis was performed using previously published transcriptome microarray data of MCC cell lines with high (WaGa and MKL1) and low (MCC13 and MCC26) miR-375 expression. Enrichment plot of the kegg_focal_adhesion signaling pathway is depicted. (c) miR-375 target genes involved in Hippo and focal adhesion signaling pathways.