Table 4.
Summary statistics of semen parameters, SDF, and ORP before and after the treatment with FH PRO for Men in idiopathic infertile patients having high SDF levels.
| Parameters | Before Treatment | n | After Treatment | n | Percent Change (Mean ± SEM) |
p Value Wilcoxon Test |
|---|---|---|---|---|---|---|
| Sperm concentration (106/mL) | 21.1 ± 16.9 (14.0; 11.0–27.0) |
51 | 32.9 ± 28.2 (27.0; 13.0-44.3) |
51 | 114.1 ± 47.0 | 0.0001 |
| Total motility (%) | 25.5 ± 12.7 (25.0; 15.0–30.0) |
51 | 32.5 ± 18.1 (30.0; 16.3–50.0) |
51 | 48.2 ± 16.5 | 0.0061 |
| Progressive motility (%) | 0.5 ± 1.8 (0.0; 0.0–0.0) |
51 | 5.5 ± 8.0 (0.0; 0.0–10.0) |
51 | 48.0 ± 11.5 | 0.0001 |
| Normal morphology (%) | 1.8 ± 1.2 (2.0; 1.0–2.0) |
51 | 2.9 ± 2.3 (2.0; 1.0–4.0) |
51 | 89.1 ± 20.8 | 0.0015 |
| SDF (%) | 56.5 ± 16.9 (55.0; 43.0–70.0) |
47 | 42.4 ± 21.2 (39.0; 27.3–56.0) |
47 | −24.2 ± 4.7 | <0.0001 |
| ORP (mV/106 sperm/mL) | 6.1 ± 6.5 (4.2; 2.5–6.9) |
51 | 3.4 ± 8.4 (1.7; 0.9–2.9) |
51 | −24.8 ± 21.1 | <0.0001 |
SDF >30% is considered as high. SDF: sperm DNA fragmentation, ORP: oxidation-reduction potential.