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HO-1 alleviates ROS generation in human hepatoma cells. (A) Fold change of ROS generation through various concentrations of H2O2 stimulation for 1 h on Hep3B–DNA and Hep3B-HO1 cells detected by DCF-DA dye. (B) The flow cytometry determined that overexpression of HO-1 blocked ROS generation stimulated by 20 μM of pyocyanin. (**, p < 0.01).
