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Ectopic overexpression of heme oxygenase-1 blocks interleukin-6 expression. The expression of HO-1 and IL-6 in Hep3B–DNA and Hep3B-HO1 cells were determined by ELISA (A), RT-qPCR (B) and reporter assays (C). Data are expressed as mean ± SE (n = 6) of luciferase activity relative to the mock-transfected group. (**, p < 0.01).
