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Effects of PEA and N-APEA in sir-2.1 mutant worms. (a) SIR-2.1 protein expression in wildtype (WT) and sir-2.1 mutant (MT) nematodes. (b) The graph displays the mean ± SEM of three independent experiments, and each group in the experiment consisted of 50 worms. The control is the group of untreated sir-2.1 mutant worms. Differences relative to the control were considered significant at * p < 0.05 and ** p < 0.01.
