Table 1.
Effects of PEA on the lifespan of C. elegans.
| Treatment | Dose (µM) |
Mean Lifespan1 (Day) |
Maximum Lifespan (day) |
Change in Mean Lifespan2 (%) | Log-Rank Test |
|---|---|---|---|---|---|
| Control | - | 11.1 ± 0.3 | 18 | / | / |
| 4-HBA | 25 | 12.7 ± 0.3 | 21 | 13.8 | *** p < 0.001 |
| PEA | 25 | 12.5 ± 0.3 | 20 | 12.4 | *** p < 0.001 |
| 50 | 13.3 ± 0.3 | 21 | 19.8 | *** p < 0.001 | |
| 100 | 13.6 ± 0.3 | 22 | 21.6 | *** p < 0.001 |
1 Mean lifespan data are presented as mean ± SEM. 2 The change in mean lifespan was calculated relative to the control group (%). Statistical significance of the difference between survival curves was determined by the log-rank test using Kaplan–Meier survival analysis. Differences relative to the control were considered significant at *** p < 0.001.