Table 2.
Effects of N-APEA on the lifespan of C. elegans.
| Treatment | Dose (µM) |
Mean Lifespan1 (day) |
Maximum Lifespan (day) |
Change in Mean Lifespan (%) | Log-Rank Test |
|---|---|---|---|---|---|
| Control | - | 11.7 ± 0.3 | 18 | - | - |
| 4-HBA | 25 | 12.7 ± 0.3 | 21 | 8.3 | ** p < 0.01 |
| N-APEA | 25 | 12.6 ± 0.3 | 21 | 7.8 | * p < 0.05 |
| 50 | 13.2 ± 0.3 | 21 | 12.6 | *** p < 0.001 | |
| 100 | 14.0 ± 0.4 | 23 | 19.9 | *** p < 0.001 |
1 Mean lifespan data are presented as mean ± SEM. 2 The change in mean lifespan was calculated relative to the control group (%). Statistical significance of the difference between survival curves was assessed by the log-rank test using Kaplan–Meier survival analysis. Differences relative to the control were considered significant at * p < 0.05, ** p < 0.01, and *** p < 0.001.