Table 3.
Multivariable Cox proportional hazards model for 3-year distant recurrence-free survival.
| Variable | Clinical Model | Weight-Loss Model | Muscle-Loss Model | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | p-Value | HR (95% CI) | p-Value | HR (95% CI) | p-Value | |
| FIGO stage | ||||||
| IB-II | Reference | Reference | Reference | |||
| III-IVA | 2.30 (1.21–4.37) | 0.01 | 2.36 (1.24–4.47) | 0.01 | 1.98 (1.05–3.74) | 0.04 |
| PLNs involvement | ||||||
| Negative | Reference | Reference | Reference | |||
| Positive | 1.75 (0.87–3.50) | 0.12 | 1.81 (0.90–3.63) | 0.10 | 2.31 (1.24–4.30) | 0.01 |
| Pathology | ||||||
| SCC | Reference | Reference | Reference | |||
| Adenocarcinoma | 4.43 (2.30–8.53) | <0.001 | 4.63 (2.40–8.94) | <0.001 | 3.03 (1.54–5.95) | 0.001 |
| SCC-Ag | 1.02 (1.01–1.02) | <0.001 | 1.02 (1.01–1.02) | <0.001 | 1.02 (1.01–1.02) | 0.001 |
| Weight change | ||||||
| Weight maintain | - | - | Reference | - | - | |
| Weight loss | - | - | 1.51 (0.76–3.02) | 0.24 | - | - |
| SMI change | ||||||
| SMI maintain | - | - | - | - | Reference | |
| SMI loss | - | - | - | - | 6.31 (3.18–12.53) | <0.001 |
| SMD change | ||||||
| SMD maintain | - | - | - | - | Reference | |
| SMD loss | - | - | - | - | 1.00 (0.53–1.87) | 0.99 |
| TATI change | ||||||
| TATI maintain | - | - | - | - | Reference | |
| TATI loss | - | - | - | - | 1.32 (0.73–2.38) | 0.36 |