Figure 2.

Structural analysis of the nucleotide-binding site on TGase2. (A) Structural comparison of TGase2 complexed with different nucleotides. Three different structures were superimposed and compared. The dotted red circle indicates the nucleotide-binding site located in between the catalytic core domain and the β-barrel1 domain. (B) Close-up view of the nucleotide-binding site on TGase2. Residues involved in the interaction with the nucleotides are shown. (C) Sequence comparison of TGase2 in various species. Residues important for binding with nucleotides are shown in red bold font.