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Meta-analysis of all intracranial aneurysm models to determine the shortest required study period for intracranial aneurysm (IA) generation. Common carotid artery (CA) ligation alone or in combination with renal artery (RA) ligation typically involved a period of several months, while intracranial aneurysms could be created by elastase injection with or without common carotid artery ligation in one month or less. Bars indicate mean + SD.
