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. 2020 Mar 23;21(6):2215. doi: 10.3390/ijms21062215

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Blocking IL-17 does not affect the survival in a mouse model of PDAC. (a) Experimental setup: Animals received anti-IL-17 antibodies on days −2, 5, 12, 19, 26, and 33. In vivo electroporation to induce pancreatic cancer was performed on day 0. (b) Mice survival (%) of the control group (n = 8) vs. anti-IL-17 treatment group (n = 11). (c) Tumor weights (including the weight of the pancreas) on day 35 (n = 3, left) and endpoint (n = 6, right). (d) The curve of body weight from the control and anti-IL-17 treatment group was recorded to monitor the potential side effect.