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. 2020 Mar 2;12(3):579. doi: 10.3390/cancers12030579

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Histopathologic credentialing of RP-MOC1 tumors. Photomicrographs of histology and immunohistochemical staining of tumor sections from the initial subcutaneous tumor and the subsequent orthotopic tumor are shown. Hematoxylin and eosin (H&E) stained sections showed invasive keratinizing moderately differentiated squamous cell carcinoma. Image was acquired at 20× magnification. Scale bar: 100 μm. Immunostaining for cytokeratin (Pan-CK) and Ki-67 showed positive staining on the membrane and nuclear staining of the epithelial cells. Immunostaining for E-cadherin and vimentin showed negative staining on the membrane and cytoplasm stain of the epithelial cells. Images were acquired at 20× magnification. Scale bar: 100 μm.