Table 1.
Patient characteristics (n = 84).
| Characteristic | Nr. (% or Range) | Site of Solitary Plasmacytoma | ||
|---|---|---|---|---|
| Extramedullary | Bone | p-value | ||
| Patients | 84 | 30 (36%) | 54 (64%) | |
| Median Age | 57 y (22–81) | 53 (22–81) | 60 (28–77) | 0.2 |
| Gender | M: 55 (65 %) F: 29 (35 %) |
22 (73%) 8 (27%) |
33 (61%) 21 (39%) |
0.3 |
| Immunohistochemical analysis | 0.3 | |||
| Kappa light chain restriction | 25 (30%) | 12 (40%) | 13 (24%) | |
| Lambda light chain restriction | 25 (30%) | 10 (33%) | 15 (28%) | |
| Both | 2 (2%) | 0 (0%) | 2 (4%) | |
| Maximum diameter | 0.16 | |||
| In cm | 4 (0.7–9.6) | 3.6 (0.7–7.9) | 4.1 (1.3–9.6) | |
| Serum Beta-2-microglobulin | 0.1 | |||
| Elevated | 4 (5%) | 1 (3%) | 3 (6%) | |
| Serum protein | 0.17 | |||
| Elevated | 7 (8%) | 2 (7%) | 5 (9%) | |
| Low | 5 (6%) | 3 (10%) | 2 (4%) | |
| Serum albumin | 0.02 | |||
| g/dL | 4.5 (2.6–5.4) | 4.6 (3.6–5.4) | 2.8 (2.6–3) | |
| Hemoglobin | 0.06 | |||
| g/dL | 13.3 (9–16.6) | 14.1 (9.6–16.6) | 13.2 (9–14.8) | |
| Serum protein immunofixation | 0.3 | |||
| Positive | 36 (43%) | 11 (37%) | 25 (46%) | |
| Negative | 29 (34%) | 13 (43%) | 16 (30%) | |
| Unknown | 19 (23%) | 6 (20%) | 13 (24%) | |
| Serum LDH | 0.13 | |||
| Elevated | 5 (6%) | 5 (17%) | 0 (0%) | |
| Bence-Jones proteinuria | 0.12 | |||
| Yes | 12 (14%) | 6 (20%) | 6 (11%) | |
| Sites of RT | <0.001 | |||
| Head and neck | 29 (34%) | 24 (80%) | 5 (9%) | |
| Thorax | 28 (33%) | 2 (7%) | 26 (48%) | |
| Abdomen | 2 (2%) | 0 | 2 (4%) | |
| Pelvis | 21 (25%) | 4 (13%) | 17 (32%) | |
| Extremities | 4 (5%) | 0 | 4 (7%) | |
M, males; F, females.