Figure 2.

Disordered microtubule-binding proteins. The dynamic nature of the CC1- and Tau-binding (dark- and light-green) behaviour suggests that both might be able to bind multiple distinct tubulin dimers (light- and dark-blue) via their individual binding motifs (light-green), thereby increasing the local tubulin concentration, connecting and stabilizing protofilaments or bundling microtubules. Image by Barth van Rossum.