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. 2020 Feb 26;9(3):197. doi: 10.3390/antiox9030197

Figure 2.

Figure 2

Effect of UT on mRNA expression in TNF-α/IFN-γ-stimulated HaCaT cells. (A) mRNA expression of IL-6, IL-8, TARC, MDC, and RANTES in HaCaT cells under TNF-α/IFN-γ-treated conditions. An equimolar quantity of mRNA was quantified compared to GAPDH: IL-6 (B), IL-8 (C), TARC (D), MDC (E), and RANTES (F). Values shown are the mean ± SD. # Significant differences from group 1 and the TNF-α/IFN-γ-induced group (# P < 0.05; ## P < 0.01; ### P < 0.001). * Significant differences from the TNF-α/IFN-γ-induced group and groups 3, 4, and 5 (* P < 0.05; ** P < 0.01; *** P < 0.001). UT, Urtica thunbergiana; TNF-α, tumor necrosis factor-alpha; IFN-γ, interferon-gamma; mRNA, messenger RNA; IL, interleukin; TARC, thymus- and activation-regulated chemokine; MDC, macrophage-derived chemokine; RANTES, regulated on activation normal T expressed and secreted; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; SD, standard deviation.