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. 2020 Feb 26;9(3):197. doi: 10.3390/antiox9030197

Figure 6.

Figure 6

Effect of UT on FLG, MAPK, IκBα, and NFATc1 expression in AD-induced NC/Nga mice. FLG, phosphorylated p38, JNK, and IκBα expression (A) and NFATc1 phosphorylation (F) were assessed by western blot analysis. Band intensities for FLG (B), p-p38 (C), p-JNK (D), p-IκBα (E), and p-NFATc1 (G) were quantified by densitometry, normalized to the level of β-actin, and calculated as a percentage of the basal response. Values shown are the mean ± SD. # Significant differences from groups 1 and 2 (## P < 0.01; ### P < 0.001). * Significant differences from groups 2, 3, 4, and 5 (* P < 0.05; ** P < 0.01; *** P < 0.001). FLG, fillagrin; MAPK, MAPK, mitogen-activated protein kinase; IκBα, inhibitor of kappa B alpha; NFATc1, nuclear factor of activated T-cells 1; AD, atopic dermatitis; JNK, c-Jun N-terminal kinase; SD, standard deviation.