Table 1.

Summary of nomenclature, expression, and localisation data of MACROD1, MACROD2, and TARG1.

Protein Name	Alternative Names	Gene Name	MW Predicted	MW Observed	Intracellular Localisation	Expression	Regulation
MACROD1	LRP16	MACROD1	35.5 kDa	27 kDa* [70,71]	Mitochondrial [40,70,71]	Ubiquitous expression, enriched in skeletal muscle [70,71]	mRNA expression is induced by oestrogen [72,73,74]
MACROD2	C20orf133	MACROD2	47 kDa	50 kDa [70]	Diffuse nuclear, cytoplasmic [70,75]	So far detected only in the brain [70,76]	Phosphorylation by ATM upon DNA damage induces translocation to cytoplasm [75]
TARG1	C6orf130	OARD1	17 kDa	17 kDa [14,70]	Nuclear, nucleolar, stress granular [14,45,70]	Ubiquitous expression [70]	Leaves nucleoli upon DNA damage [14]

* The predicted molecular weight of MACROD1 is 35 kDa. However, due to cleavage of the N-terminus upon translocation into mitochondria, the protein detected in western blotting (WB) is smaller [70].