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Progression-free and overall survival of cetuximab treated colorectal cancer patients (expressed in days) in relation to the level of EGFR protein expression defined as H-score. Kaplan–Meyer statistics. (A,B): Primary tumors (N = 88). (C,D): Metastatic tissue (N = 29). (A,C): Progression-free survival, (B,D): Overall survival in days. Low= below-, high=above HS threshold. (B): * p = 0.042, (C): * p = 0.024, ** p = 0.046, (D): * p = 0.008, ** p = 0.05, *** p < 0.018, **** p = 0.053.
