Table 3.
Multivariant analysis of various prognostic/predictive factors of cetuximab efficacy using the Cox proportional hazard model for overall survival: EGFR protein expression of the metastases (N = 29).
| Variables | p | RR (95% CI) |
|---|---|---|
| age | 0.001 | 0.916 (0.871–0.964) |
| sex | 0.427 | 1.468 (0.57–3.784) |
| EGFR-HS | 0.083 | 1.007 (0.999–1.016) |
| sidedness | 0.006 | 5.694 (1.641–19.757) |
| metastasis (S vs M) | 0.19 | 0.469 (0.151–1.455) |
Multiple metastatic disease (MM), relative risk (RR), single metastatic disease (S), sidedness = metastasis derived from the left or right-sided primary.