Skip to main content
. 2020 Feb 26;12(3):539. doi: 10.3390/cancers12030539

Figure 1.

Figure 1

C-X-C motif chemokine receptor 4 (CXCR4) transcript and protein expression in tumor and adjacent normal tissue. RT-PCR analysis of CXCR4 transcript abundance in normal and tumor tissue: (a) stromal cells and (b) colonocytes after multiple testing correction (Tukey post hoc test, Supplementary Table S1). Note the increase of CXCR4 transcripts in both tumor stromal cells and colonocytes compared to adjacent matched tissue controls (q-value < 0.05). (c) CXCR4 protein expression in tumor colonocytes (T) and normal colonocytes adjacent to tumor (adj). Note the increased CXCR4 protein expression in tumor colonocytes compared to adjacent colonocytes from normal appearing mucosa (n = 5; p-value < 0.05, paired Student’s t-test, Supplementary Table S2).