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Cellular epigenetic heterogeneity in cancer: Immunohistochemical examination of ovarian cancer tissues with an antibody against histone Histone H3 tri methyl K4 (H3K4me3) revealed different expression levels (indicated by brown staining). Specimens were attributed to negative (A), weak (B), moderate (C), and strongly positive (D) expression levels of H3K4me3 (scale bar 200 μm, small pictures 100 μm).
