Figure 3.
(A) Superimposition of two representative structures of GR(C74U) complexed with ADE and 6AP based on three nucleotides. The occupancies of hydrogen bonds (H-bonds) formed between three nucleotides and ligands are labeled. (B) Superimposition of two representative structures of GR(C74U) complexed with ADE and 6AP based on four nucleotides which interacted with ligands via a van der Waals interaction. The van der Waals interactions are labeled with distances. The ligands and nucleotides in the ADE complex are shown in a pale cyan color with stick representation. In the 6AP complex, they are shown using a stick-and-ball representation colored by elemental name. The labels in ADE and 6AP complexes are shown in pink and black colors, respectively.