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. 2020 Mar 23;12(3):758. doi: 10.3390/cancers12030758

Figure 2.

Figure 2

MeCP2 depletion does not influence the proliferation of colorectal cancer (CRC) cells in vitro and in vivo. (A) shRNA-mediated MeCP2 knockdown was determined by Western blot (left). MeCP2 silencing did not influence cell viability in HCT116 cells (right). (B) sgRNA-mediated MeCP2 knockout was determined by Western blot (left). MeCP2 knockout did not influence cell viability in HCT116 cells (right). (C) MeCP2 knockdown did not affect apoptosis of HCT116 cells. (D) MeCP2 knockout did not influence apoptosis in HCT116 cells. (E) MeCP2 knockdown did not influence the cell cycle distribution. (F) MeCP2 knockout did not affect cell cycle distribution. (G) MeCP2 knockdown did not suppress cell proliferation in vivo. (H) MeCP2 knockout did not influence cell proliferation in vivo.