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(A) Western blot against exosomal marker TSG101 from HCC44 and H23 cell lines under normoxic or hypoxic conditions. (B) Nanoparticle tracking analysis (NTA) report of the average distribution of particle size in a representative exosomal sample derived from HCC44 cells; lincRNA-p21 is overexpressed under hypoxic conditions in both (C) cell lines and (D) EVs. siRNA transfection against lincRNA-p21 under hypoxic conditions reduced its expression in both (E) cell lines and (F) EVs.
