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. 2020 Mar 23;12(3):755. doi: 10.3390/cancers12030755

Table 2.

Multivariate Cox regression analysis for relapse-free survival.

Variable adjHR 95% CI p-Value
D-loop
Age 0.75 0.27 2.15 0.598
Sex 1.01 0.97 1.05 0.672
EGFR mutation 0.99 0.35 2.79 0.985
Tumor Size 3.74 0.99 14.07 0.051
Smoking Status 1.23 0.40 3.82 0.716
D-loop mutations 0.18 0.04 0.82 0.027
Complex I
Age 0.99 0.95 1.03 0.573
Sex 0.89 0.31 2.57 0.827
EGFR mutation 0.78 0.28 2.16 0.633
Tumor Size 4.23 1.10 16.19 0.035
Smoking Status 0.99 0.32 3.04 0.983
Complex-I mutations 0.97 0.37 2.56 0.958
Complex IV
Age 0.65 0.21 2.09 0.474
Sex 0.98 0.95 1.02 0.418
EGFR mutation 0.89 0.30 2.61 0.826
Tumor Size 3.99 1.13 14.14 0.032
Smoking Status 1.49 0.46 4.75 0.505
Complex-IV mutations 3.69 1.34 10.18 0.012
Complex V
Age 0.62 0.21 1.81 0.379
Sex 0.97 0.93 1.01 0.141
EGFR mutation 0.58 0.19 1.73 0.324
Tumor Size 5.89 1.59 21.88 0.008
Smoking Status 1.05 0.32 3.37 0.941
Complex-V mutations 6.63 2.06 21.33 0.002
Complex IV and Complex V
Age 0.60 0.18 1.95 0.391
Sex 0.98 0.94 1.02 0.325
EGFR mutation 0.91 0.31 2.72 0.869
Tumor Size 4.31 1.22 15.21 0.023
Smoking Status 2.07 0.63 6.86 0.233
Complex IV and V mutations 8.63 2.52 29.57 0.001
Risk Score
Age 0.98 0.94 1.02 0.337
Sex 0.65 0.21 1.99 0.447
EGFR mutation 1.17 0.37 3.68 0.786
Tumor Size 4.03 1.11 14.66 0.034
Smoking Status 2.27 0.66 7.78 0.194
High risk group 9.10 2.93 28.32 <0.001

adjHR: adjusted hazard ratio, CI: confidence interval.