Protein-protein interaction network of 39 secreted proteins enriched in pancreatic ductal adenocarcinoma. Analysis using STRING [101] illustrates potential interactions between secreted proteins with a minimum confidence score of 0.7. Proteins in the interaction network are represented as nodes connected by lines whose thickness reflects a confidence index higher than 0.7. The top five enriched GO terms are represented by the network node colors for each protein: red, extracellular exosome; blue, membrane-bounded vesicle; green, blood microparticle; yellow, cytoplasmic membrane-bounded vesicle lumen; purple, secretory granule lumen.