Figure 5.

Metastases in the omental area. (A) PEO4 cells occupy the omentum and invade in the direction of the pancreas. Images show the positivity of the invasive metastases for p53, CA125, and HNM. Notice that the pattern of expression of cancer cells is very tight or solid. (B) Arrangement of PEO6 cells in the omental area depicts a micropapillary phenotype with multicellular structures accumulated toward the periphery of the tissue. Notice that the staining for p53 and HNM is more homogeneous than that of CA125, which is mostly expressed toward open tissue with pseudoglandular areas. Scale bars = 100 μm.