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Metastases to the ovaries. (A) PEO4 cells occupy the ovary and shows positivity for the expression of mutant p53, CA125, and HNM. (B) PEO6 cells formed a tumor within the ovary. Higher magnification shows the clear limit between the luteal tissue and the tumoral area, and the positivity of the tumor cells for p53 and CA125 ([iv,v]). Notice the p53 positive cells identifying an isolated metastasis (m) within the corpus luteum ([vi]). Scale bars = 100 μm.
