Table 1.
Relationship between chosen antibodies and single nucleotide polymorphisms (SNPs), and radiosensitivity status measured by odds ratio with 95% CI calculated in the multiple logistic regression model. The value of odds ratio for antibodies was scaled to represent the impact of a 100-unit increase, instead of a 1-unit increase.
| Predictor | Model 1 | Model 2 | Model 3 |
|---|---|---|---|
| HPA011088 - STIM1 | 1.14 (0.99;1.31) | 1.13 (1.01;1.26) * | 1.20 (1.07;1.36) * |
| HPA011325 - PDGFB | 4.36 (1.42;13.39) * | 2.37 (1.07;5.27) * | 3.86 (1.50;9.91) * |
| HPA010134 - PNKD | 1.24 (0.61;2.51) | 1.35 (0.86;2.10) | 1.38 (0.77;2.48) |
| HPA030603 - THPO | 1.06 (0.97;1.16) | 1.05 (0.99;1.12) | 1.08 (1.01;1.16) * |
| HPA010115 - CHIT1 | 1.19 (1.03;1.38) * | 1.08 (0.98;1.19) | 1.17 (1.02;1.33) * |
| HPA000909 - RP2 | 2.36 (0.65;8.60) | 1.46 (0.64;3.34) | 2.19 (0.73;6.56) |
| HPA001816 - SERPINC1 | 0.93 (0.85;1.01) | 0.95 (0.89;1.00) | 0.92 (0.86;0.99) * |
| HPA063911 - SLC4A1 | 0.74 (0.45;1.24) | 0.55 (0.36;0.83) * | 0.40 (0.23;0.71) * |
| HPA004156 - AKT1 | 2.56 (0.76;8.63) | - | - |
| HPA035034 – GCA | 0.77 (0.56;1.056) | - | - |
| HPA027066 - FN1 | 1.06 (0.96;1.17) | - | - |
| HPA064755 – FGA | 0.96 (0.89;1.04) | - | - |
| HPA051370 – FGA | 1.12 (0.99;1.27) | - | - |
| HPA027735 - DBNL | 0.29 (0.08;1.09) | - | - |
| HPA041937 - BLVRB | 1.11 (0.84;1.46) | - | - |
| HPA004819 – PGR | 0.36 (0.16;0.81) * | - | - |
| HPA051420 - PPARA | 0.74 (0.50;1.11) | - | - |
| Rs69947 – AA/AC | - | - | 1 |
| Rs69947 – CC | - | - | 0.03 (0.00;0.22) * |
* Significant predictor in the model at alpha = 0.05.