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Stability of the Cys-linker-MMAE-based ADC in 50% plasma at 37 °C. The test concentration of mil40-15 was 250 nM, and the lower limit of quantification (LLOQ) and upper limit of quantification (ULOQ) of MMAE were 2 nM and 250 nM, respectively. Each sample point contains two repetitions and the results are shown as the mean.
