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. 2009 Dec 11;2009(417):59–68. [Article in French] doi: 10.1016/S1773-035X(09)70310-7

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Copyright © 2009 Elsevier Masson SAS. All rights reserved.

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Voies de transduction du signal induites par HMGB1.

Représentation schématique des voies de transduction induites par la protéine HMGB1 extracellulaire. À ce jour, 3 voies sont décrites qui impliquent des récepteurs de la famille TLR (TLR-2, TLR-4) et le récepteur RAGE. La cascade d’activation qui va répondre à ce signal spécifique va pouvoir engager différents processus cellulaires.

D’après Gozlan et al., Bentham open e-books, 2009.