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. 2020 Apr 7;13:32. doi: 10.1186/s13045-020-00865-7

Table 1.

Anti-proliferative activity of MI130110 in CD13-positive and negative cell lines. Values represent the geometric mean of three or more different experiments, each performed in triplicate

Tumor cell line Cancer type CD13 status IC50 (μg/mL) GSD
HT1080 Fibrosarcoma Positive 0.17 1.32
NB-4 Leukemia Positive 0.10 3.5
U-937 Lymphoma Positive 0.14 3.3
RPMI 8226 Myeloma Negative > 1.0 -
Raji Lymphoma Negative > 1.0 -

. IC50 concentration that inhibits cell growth by 50%, GSD geometric standard deviation