Table 2.

Selected pharmaceuticals derived from filamentous fungi and their applications. (Modified after [13])

Pharmaceutical	Remark
β-lactams	Penicillins and cephalosporins account for more than 30% of the global antibiotics market
Cyclosporin	Immunosuppressant that avoids organ rejection in transplant surgery
Drospirenone	Steroid hormone used as a birth control pill and traded as Slynd; in combination with an oestrogen traded under the brand name Yasmin
Echinocandins	Caspofungin, micafungin and anidulafungin used for the treatment of Candida infections
Griseofulvin	Antifungal used for the treatment of skin infections
Mycophenolic acid	Immunosuppressant that avoids organ rejection in transplant surgery and is traded as CellCept
Myriocin	Chemical analogue thereof is used to treat multiple sclerosis; approved in 2018 as Gilenya
Psilocybin	Indolalkaloid currently being tested in phase II clinical trials for the treatment of major depressive disorders and is considered by the FDA as a breakthrough therapy [16]
Statins	Lovastatin, simvastatin and pravastatin are used to treat cardiovascular diseases by lowering cholesterol levels