Figure 1.

Mutation of the Lam gene induces mortality during adult eclosion, which is increased by a gypsy insertion in the euchromatic cut locus. Mortality during adult eclosion of pharate with different genotypes. Column 1: flies with X chromosomes from the wild type Canton S (wt) strain. Columns 2–10: flies with X chromosomes carrying the flamenco permissive allele flam^A, which allows gypsy activation. These flies can have the gypsy induced mutation (ct^A) in heterozygosis, in homozygosis/hemizygosis, or the wild type allele (+). Flies can be homozygous for the wild type Lam allele (+/+), heterozygous for one of the two loss-of-function Lam alleles (4643/+ or +/K2) or transheterozygous (4643/K2). Y: Y chromosome. Asterisk: females and males derived from the same genetic cross. Data are mean values from three independent experiments, and error bars indicate SD (* P < 0.05).