Skip to main content
. 2020 Feb 26;9(3):549. doi: 10.3390/cells9030549

Figure 1.

Figure 1

Histopathological features of the bone marrow (BM) of patients with rheumatoid arthritis (RA) (a–d) and osteoarthritis (OA) (e–h). (a) Nodular lymphocytic infiltration with germinal center formation (hematoxylin and eosin [H&E] stain, 100×). (b) CD3+ T cells in the marginal and mantle zone. (c) CD4+ T cells in the lymphoid follicle. (d) Nuclear expression of FOXP3 in cells localized in the lymphoid follicle. (b–d: EnVision stain, 100×). (e) H&E staining shows visible nodular lymphocytic infiltration, 100×. (f,g) Most of the lymphocytes in the lymphoid follicle revealed CD3 and CD4 expression. (h) FOXP3 in nuclear localization in cells of the lymphoid follicle (f–h: EnVision stain, 100−). Scale bar, 20 μm. Histology staining was done on five patients in each group while one representative is shown.