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. 2020 Feb 28;9(3):569. doi: 10.3390/cells9030569

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Aspirin mitigated tumor growth in obese mice. LLC cells (LLC) were implanted into the lean (ND) and obese (HFD) mice and grew for 3 weeks. Three days after implantation, aspirin (20 mg/kg) was administrated daily up until the end of the experiment. The tumor volume (A) and tumor mass (B) were weighed and analyzed. The representative resected tumors are shown (B). Proteins were extracted from the resected tumor tissues and subjected to Western blot with indicated antibodies. Representative blot is shown (C). Quantitative data are depicted and the content in ND was defined as 100%. * p < 0.05 vs. ND and # p < 0.05 vs. HFD (n = 6 per group).