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Adenosine deaminase (ADA, 0.5 U/mL) decreases the viability/proliferation (MTT assay, A) of human subcutaneous fibroblasts (HSCF) without modifying collagen production (Sirius Red assay, B). Boxes and whiskers represent pooled data from at least three different individuals; 4–6 replicas were performed for each individual. ** p < 0.01 (one-way ANOVA) represent significant differences compared to control conditions in the same individual.
