Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 4;9(3):613. doi: 10.3390/cells9030613

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Binding interactions shown between SN-38 (left) and SCO-201 (right) to the transporter BCRP. Both molecules interacted with the PHE-439 residue of the B chain of BCRP. The interaction percentages indicate accounting for number of frames over the 10 ns simulation where the binding was present. Timetable of ligand–protein interactions are available in Figures S7 and S8. Interactions shown were present in over 30% of the simulation frames. Graphical representation was produced using Desmond, Schrödinger, 2019-3, LLC [43].