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. 2020 Mar 4;9(3):620. doi: 10.3390/cells9030620

Figure 4.

Figure 4

Response of downstream signaling to Frk stimulation in hiPSCs. (A) The expression levels of genes involved in cAMP signaling in U2OS cells and hiPSCs. Data are presented as the means ± SEM relative to U2OS; n = 4 for each comparison. * p < 0.05, ** p < 0.01 versus the corresponding control. (B) and (C) Phosphorylation of CREB by Frk stimulation in hiPSCs, BJ, and U2OS cells. Right graph shows quantified levels of p-CREB / total CREB from left blots, respectively. Data are presented as the means ± SEM relative to each 0 h.