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. 2020 Mar 19;9(3):751. doi: 10.3390/cells9030751

Figure 3.

Figure 3

(A) Gene expression of the bone metastatic gene IBSP is lower in RUNT KO cells than in WT melanoma cells. Accordingly, there is a lower percentage of BSP-positive cells (B) and lower levels of the BSP protein (C) in RUNT KO cells compared to WT melanoma cells. Gene expression levels of the bone metastatic genes SPP1 (D) and CD44 (E) are lower in RUNT KO cells than in WT melanoma cells. (* p < 0.05; # p < 0.01); magnification 40X.