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Serum cytokine levels and renal mRNA expression related to interleukin (IL)-6 and IL-17A cytokine signaling. (A) Serum IL-6 and IL-17A concentrations (pg/mL) in adult (4 to 10 months old) wild type (WT) (n = 11–15) and MRL/lpr Fli-1+/− mice (n = 15 per group). (B) Relative expression of cytokines and related signaling molecules in the kidney of adult (4 to 9 months old) MRL/lpr Fli-1+/− (n = 3–11) vs. WT mice (n = 4–13); * p < 0.05 is considered as significant.
