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. 2020 Mar 13;9(3):707. doi: 10.3390/cells9030707

Figure 3.

Figure 3

The effect of various culture conditions or treatment on the stem cell-derived EVs. Cell density, cell phenotype, hypoxia treatment, inflammatory stimuli, drug preconditioning, and three-dimensional (3D) culture influence the production and capabilities of extracellular vesicles (EVs). LPS, lipopolysaccharide; DIM, 3,3′-Diindolylmethane; MVB, multivesicular bodies.