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. 2020 Mar 9;9(3):662. doi: 10.3390/cells9030662

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Germ-cell granules or ‘P-bodies’ in young mouse oocytes and a sub-cortical mRNA storage domain in growing/mature oocytes. Confocal images of mouse oocytes from 2 days postpartum (dpp) and 12 dpp females, immature NSN (non-surrounded nucleolus) and mature SN (surrounded nucleolus) GV oocytes, MII oocytes, and cumulus cells from adult females after staining with 18,033 (stains P-body protein EDC4), DCP1A, and DDX6 antibodies. Diagonal arrowheads depict P-bodies and horizontal arrowheads depict subcortical aggregates. Dashed lines border the subcortical domain. Staining with 18,033 is green, other proteins are red, and DNA staining in blue. Scale bars: 10 μm. Source: Flemr et al., 2010 [28].