Figure 6.

ASC-exosomes restore oxazole-induced defects in the lamellar secretory system. Electron micrographs of epidermis. Inserts show high magnification of lamellar bodies and/or processed lamellar lipids as indicated. Note that lamellar bodies are more abundant at the SG-SC interface in the ASC-exosomes treated group compared with the vehicle and dexamethasone groups. KHG: keratohyaline granules, C: corneocyte, arrows: lamellar bodies, arrow heads: lipid secretion points, *: lipid phase separation (indicating incomplete processing). Scale bar: 100 nm.