Why carry out this study?

HyQvia offers distinct advantages for the treatment of PID, but the current prescribing guidelines do not specify the range of administration options needed to optimize care in all patients, and little data is published on its use in pediatrics.

A need exists to examine clinical practice experience with administration of HyQvia at variance with current guidelines and use in children.

The current analysis sought to identify and characterize real-world use of alternative HyQvia regimens in adults as well as HyQvia use in pediatric patients.

What was learned from the study?

HyQvia may be used in adults requiring alternative ramp-up and dosing schedules and may be especially well suited to use in children.

The most notable variations included shorter ramp-up periods, use of two rather than one infusion site, and slower than maximum permitted infusion rates to mitigate local adverse events (AEs).

Four of the five pediatric patients reported no AEs, and only one discontinued therapy.