Fig. 1.

Examples of mean sensitivity (MS) with Humphrey Matrix frequency doubling technology (FDT) 10-2 strategy in two patients with type 1 diabetes with mild signs of non-proliferative diabetic retinopathy. One patient (DP EYE# 4) was treated with placebo (3 drops/day), and one patient (DC EYE# 2), with citicoline and vitamin B₁₂ (3 drops/day) for 36 months of follow-up. With respect to baseline, at the end of follow-up (36 months), worsening of MS values was observed in DP EYE, while no significant changes of those in DC EYE were observed