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. 2020 Feb 22;37(4):1479–1495. doi: 10.1007/s12325-020-01258-5

Table 3.

Patient and rheumatologist DCE results

Attribute Level Patients (n = 137) Rheumatologists (n = 90)
Partial utility SE p value* Partial utility SE p value*
Time with optimal QoL 1 year 0.244 0.036 < 0.001 0.195 0.045 < 0.001
10 years 2.44 1.951
7 years 1.708 1.366
5 years 1.22 0.976
2 years 0.488 0.39
Substantial improvement of RA symptoms 1% patientsa 0.003 0.003 0.251 0.015 0.004 < 0.001
9 out of 10 patients (90%) 0.303 1.35
7 out of 10 patients (70%) 0.235 1.023
5 out of 10 patients (50%) 0.168 0.731
3 out of 10 patients (30%) 0.101 0.438
Onset of treatment action 7 days (ref) 0.000 0.000
15 days − 0.372 0.285 0.193 − 0.602 0.356 0.091
1 month − 0.562 0.255 0.027 − 1.083 0.326 0.001
3 months 0.194 0.275 0.481 − 0.715 0.342 0.036
Severe adverse events 1% patientsa − 0.156 0.058 0.007 − 0.182 0.074 0.014
1 out of 100 patients (1%) − 0.156 − 0.182
5 out of 100 patients (5%) − 0.781 − 0.908
Mild adverse events 1% patientsa 0.003 0.014 0.856 − 0.014 0.018 0.444
10 out of 100 patients (10%) 0.025 − 0.139
30 out of 100 patients (30%) 0.076 – 0.416
Mode of administration Daily Oral (ref) 0.000 0.000
Weekly subcutaneous − 1.394 0.372 < 0.001 − 1.683 0.461 < 0.001
Monthly subcutaneous − 0.375 0.364 0.302 − 0.249 0.442 0.574
Monthly intravenous − 0.956 0.366 0.009 –  0.446 0.458 0.331
Additional cost/month for treatment Additional 1€/month − 0.012 0.007 0.102 – 0.009 0.009 0.296
0 0 0
10 − 0.119 –  0.092
20 − 0.238 − 0.185
50 − 0.594 − 0.462

Bold values indicate that there is statistical significance (p < 0.05)

QoL quality of life, RA rheumatoid arthritis, SE standard error

aRefers to a 1% of increase of the proportion of patients