Community-acquired pneumonia (CAP) is a major health concern, because it is a very frequent and deadly condition.

CAP etiology is changing owing to the recognized importance of viruses, pneumococcal and influenza vaccines.

New drugs were developed to treat CAP; however, most of them focus on non-severe CAP.

Despite the frequency of CAP, several recommendations are based on low quality evidence. We have therefore defined several unmet clinical needs to promote research on CAP.