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. 2020 Mar 24;9(3):785. doi: 10.3390/cells9030785

Table 1.

Adenosine receptor drugs in respiratory diseases.

Receptors	Diseases	Drugs
Receptors	Diseases	Selective Full Agonist	Antagonist/Partial Agonist
A₁AR	COPD and asthma		L-97-1 [87] EPI-2010 [88]
A₁AR	Lung injury	CCPA [91]
A_2AAR	COPD and asthma	CGS-21680 [109] UK371,104 (DC) [110] GW328267X (DC) [111] Regadenoson [112] Apadenoson [59]
A_2AAR	Lung injury	CGS-21680 [113] PTX [114]
A_2BAR	COPD and asthma	BAY 60-6853 [115]	CVT-6883 [116] CGS15493, WO-00125210, and ATL-907 [86]
	Lung injury	BAY 60-6583 [117]
	Fibrosis and interstitial lung diseases	GS-6201 [118]	CVT-6883 [119] QAF 805 [85]
A₃AR	COPD and asthma		QAF 805 [85]
A₃AR	Lung injury	IB-MECA [120]

DC = discontinued.